Mexico City’s mayor said late on Wednesday (September 10, 2025) that three people had died and 70 were injured in the explosion of a gas tanker truck along a major Mexico City highway.

Mayor Clara Brugada called the explosion under a highway overpass an “emergency” that burned 18 vehicles and left 19 of those injured in grave condition.

A drone view shows emergency personnel working at the site of a gas tanker explosion on Ignacio Zaragoza Avenue, where multiple individuals sustained burn injuries after the vehicle overturned, in Mexico City, on September 10, 2025.
| Photo Credit:
Reuters

Ms. Brugada said prosecutors were investigating, but it appeared that the truck exploded after it tipped over on the highway.

The massive blast and fire engulfed several vehicles near the border between the capital’s Iztapalapa district and Chalco in neighboring Mexico State. Drone footage showed firefighters battling the flames and cooling the charred remains of the tanker and nearby vehicles.

“We will continue to provide medical support to the victims of this incident,” she said.

Emergency personnel responded to the scene, where several people sustained serious burn injuries, according to local officials. The city’s fire department later said the flames had been fully extinguished in and around the overturned tanker trailer, which had been hauling liquefied petroleum gas.

This incident marks the second major accident on highways in Mexico this week.